The INTEGRATE project

The INTEGRATE study compared traditional diagnostic methods with modern, sensitive molecular and genomic microbiological methods for identifying and characterising responsible pathogens. This study provides Illumina paired-end data, generated by next-generation sequencing of the stool of 1,067 symptomatic patients. These data include paired metagenomic (DNA) and metatranscriptomic (RNA) data generated from the stool of 985 patients. Data from the remaining 82 stool samples (32 with metagenomic data only, and 50 with metatranscriptomic data only) are also included. The MetaWRAP read_qc module was used to remove low-quality, adapter, and human sequences from all paired-end reads by. Human sequences were removed via alignment to the T2T consortium complete human genome, (GCF_009914755.1) and human mitochondrial genome (NC_012920.1).