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Rat catechol O-methyltransferase in complex with a catechol-type, N6-propyladenine-containing bisubstrate inhibitor

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Protein Data Bank Japan2024-03-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3hvj
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Rat catechol O-methyltransferase in complex with a catechol-type, N6-propyladenine-containing bisubstrate inhibitor Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Catechol O-methyltransferase, ... Authors: Ehler, A, Schlatter, D, Stihle, M, Benz, J, Rudolph, M.G. Deposit date: 2009-06-16 Release date: 2009-10-13 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Molecular recognition at the active site of catechol-o-methyltransferase: energetically favorable replacement of a water molecule imported by a bisubstrate inhibitor. Angew.Chem.Int.Ed.Engl., 48, 2009
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2009-06-16
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