Effect of JAK blockade on IFNa response in B cells in vitro
收藏官方服务：
资源简介：
Effect of JAK blockade on IFNa response in B cells in vitro
应用场景：
创建时间：
2016-07-20
相关数据集
Analysis of germinal centers in UNG and AID deficient mice
Analyze kinetics, cell composition and proliferation of germinal center B cells in wt vs Ung-/- vs Aicda-/- vs Ung-/- Aicda-/- mice after immunization with model antigens.
NIAID Data Ecosystem80
Maintenance of haematopoietic stem cells by tyrosine-unphosphorylated STAT5 and JAK inhibition - STAT5 deficient HSPCs (LK). Maintenance of haematopoietic stem cells by tyrosine-unphosphorylated STAT5 and JAK inhibition - STAT5 deficient HSPCs (LK)
Adult haematopoietic stem cells (HSCs) are responsible for the lifelong production of blood and immune cells and must respond to extracellular cues including cytokines. The JAK/STAT pathway is a highl
NIAID Data Ecosystem20
Table 1_JAK/STAT in human diseases: a common axis in immunodeficiencies and hematological disorders.pdf
The JAK-STAT signaling pathway (Janus Kinase-Signal Transducer and Activator of Transcription) is a crucial molecular cascade that regulates immune responses, cell proliferation, and hematopoiesis. Ge
NIAID Data Ecosystem10
TET enzymes augment AID expression via 5hmC modifications at the Aicda superenhancer [H3K27ac_ChIP-seq]. TET enzymes augment AID expression via 5hmC modifications at the Aicda superenhancer [H3K27ac_ChIP-seq]
TET enzymes are dioxygenases that promote DNA demethylation by oxidizing the methyl group of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). Here we report a close correspondence between 5hm
NIAID Data Ecosystem50
Similarities in gene-expression changes induced by EBV and CD40L/IL4.
*Numbers in parentheses indicate the number of genes within the gene-set. Note that for one gene (ZNF487P), one probe-set was up- regulated and one was down-regulated by EBV compared to resting B cell
Figshare2015-12-02 更新10
