Cross-disease comparisons of 8 validated salivary mRNA biomarkers.

NOTE: All analysis and comparison were based on microarray data. The validated mRNA biomarkers for breast cancer detection were checked against other microarray datasets (see text). Briefly, t-test p-values were calculated for all breast-cancer-validated genes in the other microarray datasets to check for significant variation (* after Bonferonni correction, P<0.006) between patients and controls in those diseases. Sample sizes of these microarray studies were 10 vs. 10 for oral cancer, 10 vs. 10 for lung cancer, 12 vs. 12 for pancreatic cancer, 11 vs. 11 for ovarian cancer, 13 vs. 13 for diabetes, 8 vs. 10 for pSS, and 10 vs. 10 for breast cancer.