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Complex structure of CDK2/Cyclin E1 and a potent, selective small molecule inhibitor

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Protein Data Bank Japan2024-11-20 更新2026-04-19 收录
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Complex structure of CDK2/Cyclin E1 and a potent, selective small molecule inhibitor Descriptor: (1R,3S)-3-{3-[(pyridin-2-yl)amino]-1H-pyrazol-5-yl}cyclopentyl propan-2-ylcarbamate, Cyclin-dependent kinase 2, G1/S-specific cyclin-E1 Authors: Ren, X. Deposit date: 2022-10-18 Release date: 2023-02-22 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Accelerated Discovery of Macrocyclic CDK2 Inhibitor QR-6401 by Generative Models and Structure-Based Drug Design. Acs Med.Chem.Lett., 14, 2023
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2022-10-18
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