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Identifying regulators of parental imprinting by CRISPR/Cas9 screening in haploid human embryonic stem cells

ChEBI2021-10-21 更新2026-07-12 收录

CRISPR/Cas9基因编辑

细胞表观遗传调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-11014 数据链接链接失效反馈

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资源简介：

Identifying regulators of parental imprinting by CRISPR/Cas9 screening in haploid human embryonic stem cells

应用场景：

创建时间：

2021-10-21

细胞表观遗传调控

胚胎谱系分化机制

The first lineage choice made in human embryo development separates trophectoderm from the inner cell mass, which proceeds to form the pluripotent epiblast and primitive endoderm. Trophectoderm on the

NIAID Data Ecosystem80

Complete RIP-seq g:Profiler results.

RNA-蛋白质互作组学

细胞表观遗传调控

DND1 is essential to maintain germ cell identity. Loss of Dnd1 function results in germ cell differentiation to teratomas in some inbred strains of mice or to somatic fates in zebrafish. Using our kno

Figshare2023-03-01 更新60

Genome-wide analysis of HMGA2 and H3K27me3 deposition in neocortical neural stem cells and transcriptome of Wild Type and Ring1 KO neocortical neural stem cells. Mus musculus

细胞表观遗传调控

胚胎皮层发育转录组

We examined the dynamic changes of H3K27me3 and gene expression in neocortical neural stem cells directly isolated from various stages of embryonic brains. ChIP-seq of HMGA2 protein in the early stage

NIAID Data Ecosystem40

Epigenetic and chromatin profiling of wild-type and Dnmt3a-deficient B1 and B2 B cells. (CUT&RUN)

细胞表观遗传调控

B细胞发育分子机制

We have comprehensively interrogated wild type B1 and B2 B lineage cells and their progenitors. In mice bearing a conditional deletion of Dnmt3a in the B lineage, we integrated a variety of whole-geno

NIAID Data Ecosystem70

Abundance of piRNAs mapping to ED-SL and EI-SL.

piRNA表达

细胞表观遗传调控

The abundance of piRNAs mapping to ED-SL or EI-SL obtained from the small RNA-seq analysis of triplicate samples of the WT ovary or the enok mutants are shown. The unique reads mapping to each ED-SL o

Figshare2021-02-01 更新40

Identifying regulators of parental imprinting by CRISPR/Cas9 screening in haploid human embryonic stem cells

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