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Final patient data sheet.

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Figshare2025-04-15 更新2026-04-28 收录
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BackgroundThere are limited studies on the prevalence of diabetic peripheral neuropathy (DPN) and related foot deformities in patients with T2DM from India.AimTo investigate the prevalence, characteristics, and risk factors for foot deformities in Asian-Indian individuals with T2DM and DPN.MethodsWe analyzed 4290 patients (32.3% female, 67.7% male, mean age 51.1 ± 9.3 years) using a cross-sectional, retrospective observational method, focusing on signs and symptoms of foot complications and neuropathy.ResultsDry Skin (44%), infection (19.7%), and ingrown toenails (16.6%) were the foremost prevalent foot health conditions. The most common neuropathic symptoms were burning (35.4%), muscle cramps (31.5%), and loss of sensation (26.6%). Multivariable logistic regression analysis identified nephropathy (OR 3.96 [95% CI: 3.02–5.20]), retinopathy (OR 3.85 [95% CI: 2.72–5.48]), coronary disease (OR 3.48 [95% CI: 2.42–5.04]), COVID-19 history (OR 2.37 [95% CI: 1.73–3.26]), smoking (OR 2.13 [95% CI: 1.56–2.91]), hypertension (OR 2.10 [95% CI: 1.63–2.73]), dyslipidemia (OR 2.09 [95% CI: 1.62–2.69]), alcohol use (OR 1.57 [95% CI: 1.14–2.15]), and high HbA1c (OR 1.29 [95% CI: 1.16–1.42]) as significant predictors (p ConclusionThis study revealed a significant incidence of foot deformities and neuropathic symptoms in Indian T2DM patients, influenced by various lifestyle and medical factors. The lack of correlation between diabetes duration and foot complications in the present study highlights the need for enhanced diabetes management and early detection strategies in India.
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2025-04-15
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