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Gefitinib sensitivity in NSCLC cell lines

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE4342
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Eleven NSCLC cell lines with widely divergent gefitinib sensitivities were compared using gene expression. Genes associated with gefitinib response were used to classify additional NSCLC lines with unknown gefitnib sensitivity. A subset of the test set data was tested for gefitinib sensitivity, and results correlated strongly with the gene expression-based predictions All eleven training set lines, and seven test set lines had both HGU133A and B chips done, while other test set lines had only HGU133As. Keywords: cell response comparison Baseline (unstimulated) gene expression was measured in a large panel of NSCLC cell lines
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2019-08-20
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