IGFR-1R complex with a pyrimidine inhibitor.
收藏Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5fxr
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资源简介：
IGFR-1R complex with a pyrimidine inhibitor. Descriptor: 5-chloranyl-4-imidazo[1,2-a]pyridin-3-yl-N-(3-methyl-1-piperidin-4-yl-pyrazol-4-yl)pyrimidin-2-amine, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR Authors: Degorce, S, Boyd, S, Curwen, J, Ducray, R, Halsall, C, Jones, C, Lach, F, Lenz, E, Pass, M, Pass, S, Trigwell, C, Norman, R, Phillips, C. Deposit date: 2016-03-02 Release date: 2016-10-19 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R). J. Med. Chem., 59, 2016
创建时间：
2016-03-02
