Dengue seroprevalence and its socioeconomic determinants in Faisalabad, Pakistan: a cross-sectional study

Abstract INTRODUCTION: Socioeconomic disparities in the community make some groups more vulnerable to dengue infection. METHODS: Fourteen dengue cases (IgM positive) served as index cases for the positive geographic cluster investigations. RESULTS: Of 292 individuals, the overall dengue seroprevalence was 22.9% (IgM positive 4.8%; IgG positive 18.1%). The highest (45%) seroprevalence was reported in the most socioeconomically vulnerable lower class, followed by the middle class (39%). Orthogonal comparisons showed that socioeconomic factors play a significant role in the prevalence of dengue. CONCLUSIONS: An integrated approach is required to control the menace through vector control strategies and improvement of socioeconomic conditions.

【摘要】
引言：社区中的社会经济差异致使部分群体更易感染登革热。
方法：14例登革热免疫球蛋白M（IgM）阳性病例作为阳性地理聚集性调查的指示病例。
结果：在292名研究对象中，登革热总体血清阳性率为22.9%（其中IgM阳性占4.8%，免疫球蛋白G（IgG）阳性占18.1%）。社会经济地位最弱势的下层阶级血清阳性率最高，达45%，其次为中产阶级（39%）。正交比较分析显示，社会经济因素对登革热流行率具有显著影响。
结论：需采取综合防控策略，通过媒介生物防制手段并改善社会经济条件，以遏制登革热这一公共健康威胁。