Dataset from: "Plasticity in voltage-gated ion channels following overwintering in respiratory motoneurons of American bullfrogs"
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<b>For a full description of the methods, please check the original paper. </b>Below, please find a description of the files' content.<br>Files on firing rates: Hypoglossal_firing rate, Fast vagus_firing rate, Slow vagus_firing rateTreatment: control and overwintered frogsCurrent: input current (in picoamperes: pA) utilized during current clamp experiments to elicit neuronal firing ratesFiring rate: neuron firing rate (in hertz: Hz) elicited by each input current used<br><br>Files on membrane properties: Hypoglossal_membrane properties, Fast vagus_membrane properties, Slow vagus_membrane propertiesTreatment: control and overwintered frogsResting potential: membrane resting potential (in millivolts: mV)Input resistance: membrane input resistance (in mega Ohm: MΩ)<br><br>Files on latency and rheobase: Hypoglossal_latency and rheobase, Fast vagus_latency and rheobase, Slow vagus_latency and rheobaseTreatment: control and overwintered frogsLatency: latency for first spike (in milli seconds: ms) after current stimulationRheobase: minimum current (in pico amperes: pA) necessary to elicit a spike in the measured neuron<br><br>Files on Calcium currents: Hypoglossal_Ca currents, Fast vagus_Ca currents, Slow vagus_Ca currentsTreatment: control and overwintered frogsVoltage: voltage (in millivolts: mV) used in voltage clamp experiments eliciting measured currents Peak current: current (in pico amperes normalized by capacitance: pA/pF) measured at the peak responseSteady state current: current (in pico amperes normalized by capacitance: pA/pF) measured after the current reached a steady state<br><br>Files on Potassium currents: Hypoglossal_K currents, Fast vagus_K currents, Slow vagus_K currentsTreatment: control and overwintered frogsVoltage: voltage (in millivolts: mV) used in voltage clamp experiments eliciting measured currents Total current: total potassium current (in pico amperes normalized by capacitance: pA/pF) measuredHigh threshold current: high threshold potassium current (in pico amperes normalized by capacitance: pA/pF) measuredA-current: potassium A-current (in pico amperes normalized by capacitance: pA/pF), calculated by subtracting high threshold currents from total current<br><br>Files on sodium persistent inward currents (NaPIC): Hypoglossal_Na persistent inward currents, Fast vagus_Na persistent inward currents, Slow vagus_Na persistent inward currentsTreatment: control and overwintered frogsHolding current: in pico amperes normalized by capacitance (pA/pF)Current amplitude: difference between the holding current and the peak response (in pico amperes normalized by capacitance: pA/pF)Peak voltage: voltage (in milli volts: mV) where the current peak response was identifiedVoltage sensitivity: the slope (in pico amperes over milli volts: pA/mV) of the change in current (in pico amperes: pA) by the change in voltage (in milli volts: mV)
提供机构:
Saunders, Sandy E.; Santin, Joseph M.; Gray, Michael; A. Viteri, José; Filogonio, Renato
创建时间:
2025-03-17



