PCL compounds excluded due to toxicity in uninfected cells.

The toxicity of the PCL compounds in absence of infection was evaluated by PrestoBlue viability assay. Compounds are indicated by their PCL catalogue ID (PCL_ID) and names (compoundName). Compounds were classified as toxic, when their normalized value for all replicates was higher than the average +3σ of the DMSO negative control for the corresponding plate. Scores and score standard deviation (scoreSD) of toxic PCL compounds are listed. The PrestoBlue raw data are available at idr0081/3-Screen/Analysis/Toxicity.xls.本研究采用PrestoBlue细胞活力检测法，评估了无感染条件下PCL化合物的毒性。所有化合物均通过其PCL目录编号（PCL_ID）与化合物名称（compoundName）进行标识。当某化合物的所有重复实验归一化值均高于对应培养板中二甲基亚砜（DMSO）阴性对照组的平均值与3倍标准差（3σ）之和时，该化合物即被归类为有毒性化合物。本列表同时列出了有毒性PCL化合物的评分值及其评分标准差（scoreSD）。PrestoBlue原始数据可从idr0081/3-Screen/Analysis/Toxicity.xls获取。