Supplementary_material: Prognostic significance and function of minichromosome maintenance protein 10 in human hepatocellular carcinoma.docx

Supplementary
Figure 1

Data for MCM10
expression in HCC from online databases. (A) The
transcription level of MCM10 in 20 different types of human cancers
(ONCOMINE). Color is determined by the highest gene rank percentile genes
based on log fold-change; red represents upregulation and blue indicates
downregulation. Cut-off of P-value and fold change were as following: P-value:
0.05, fold change: 1.5, gene rank: 10%, data type: mRNA. (B) Relative
expression of MCM10 in HCC tissues (n = 371) and adjacent normal liver
tissues (n = 50) from TCGA database (UALCAN). (C) Relative expression
of MCM10 in normal individuals (n = 50) and in HCC patients with different
cancer stages (Stage 1, n = 168; Stage 2, n = 84; Stage 3, n = 82; Stage 4, n
= 6). *P < 0.05, **P < 0.01, ***P < 0.001. (D)
Representative immunohistochemistry images of MCM10 protein in HCC tissues
and normal liver tissues (Human Protein Atlas).

Supplementary Table 1

Clinicopathological
characteristics of 364 HCC patients.

Supplementary Table
2

Estimated
AUC value of TNM and MCM10 in 364 HCC patients after follow-up.

Supplementary Table
3

Summary
of significantly enriched GO annotations of MCM10 related network.