Chami, J. Synthesis Optimisation of the Triazolopyrazine Series
收藏数据链接：
官方服务：
资源简介：
Jason Chami, Open Source Malaria paper 2015
应用场景：
创建时间：
2015-08-19
相关数据集
Structure–Activity Relationship Studies of a Novel Class of Transmission Blocking Antimalarials Targeting Male Gametes
Malaria is still a leading cause of mortality among children in the developing world, and despite the immense progress made in reducing the global burden, further efforts are needed if eradication is
NIAID Data Ecosystem70
Mechanism of Cobalt-Catalyzed Heterodimerization of Acrylates and 1,3-Dienes. A Potential Role of Cationic Cobalt(I) Intermediates
Coupling reactions of feedstock alkenes are promising, but few of these reactions are practiced industrially. Even though recent advances in the synthetic methodology have led to excellent regio- and
NIAID Data Ecosystem20
High-Throughput Salt Screening of Synthetic Intermediates: Effects of Solvents, Counterions, and Counterion Solubility
Using a statistical Z-score methodology, the yield data from 65 high-throughput acid screens and 45 base screens on synthetic intermediates were analyzed. The results show that salt screening outcomes
NIAID Data Ecosystem10
Design and Synthesis of Orally Bioavailable Piperazine Substituted 4(1 H )‑Quinolones with Potent Antimalarial Activity: Structure–Activity and Structure–Property Relationship Studies
Malaria deaths have been decreasing over the last 10–15 years, with global mortality rates having fallen by 47% since 2000. While the World Health Organization (WHO) recommends the use of artemisinin-
NIAID Data Ecosystem40
Optimization of Prodiginines as Single-Dose Curative Antimalarials
The emergence of drug-resistant malaria underscores the urgent need for novel, well-tolerated antimalarials with multistage activity and distinct mechanisms of action. Here, we report the design and s
Figshare2025-11-18 更新10
