five

Irf3 phenotyping

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE77600
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The interferon regulatory factors IRF3 and IRF7 are key players in the regulation of type I and III IFN genes. In this study, we analyzed the role of IRF3 and IRF7 for the host response to influenza A virus infections in Irf3-/-, Irf7-/- and Irf3-/-Irf7-/- knock-out mice. The KO and WT mice were intranasally infected with PR8M virus or PBS for mock controls. Lungs were collected at indicated time points post infection (d3) . Total RNA from these lungs were used for microarray analysis.
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2017-11-01
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