MicroRNA Expression Profiles Analysis in Mouse Pancreatitis Tissue With or Without Hypertriglyceridemia. MicroRNA Expression Profiles Analysis in Mouse Pancreatitis Tissue With or Without Hypertriglyceridemia

The crucial roles of miRNAs have been implicated in various pathological processes, including pancreatitis. However, roles of miRNAs in hypertriglyceridemia-associated pancreatitis have not been reported. Pancreatitis tissue from mice with or without hypertriglyceridemia were analyzed for microRNA profiling. Using qPCR verification, we further identified miR-153 as the most upregulated miRNA in mice with hypertriglyceridemia. This work provide potential therapeutic targets for the treatment of hypertriglyceridemia-associated pancreatitis. Overall design: Pancreatitis tissue from mice with or without hypertriglyceridemia were used for microRNA sequencing.