A haploid gene-trap mutant collection enables functional genetics in human cells

ChEBI2013-12-31 更新2026-07-21 收录

基因功能

单倍体细胞遗传学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-47428 数据链接链接失效反馈

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资源简介：

A haploid gene-trap mutant collection enables functional genetics in human cells

创建时间：

2013-12-31

Fh1

基因功能

代谢过程

Enables fumarate hydratase activity. Involved in several processes, including fumarate metabolic process; positive regulation of cold-induced thermogenesis; and tricarboxylic acid cycle. Acts upstream

rgd.mcw.edu540

Tmprss6 modulates radiation-induced liver injury through the hepcidin axis and PI3K/AKT pathway

基因功能

信号通路

Radiation-induced liver injury (RILI) poses a significant challenge in abdomino-pelvic tumor radiotherapy, adversely impacting normal liver tissues. This study explores the role of Tmprss6 , a g

Taylor & Francis Group2025-07-24 更新70

Dataset: A genetic screen identifies C. elegans eif-3.H and hrpr-1 as pro-apoptotic genes and potential activators of egl-1 expression

基因功能

细胞凋亡

egl-1 activator candidates

DataCite Commons2024-02-16 更新30

Bxy-fuca encoding α-L-fucosidase plays crucial roles in development and reproduction of the pathogenic pinewood nematode, Bursaphelenchus xylophilus.

基因功能

生物生殖发育

通过RNA干扰研究了一个与致病相关的fuca基因在松材线虫中的功能。胚胎期fuca基因被干扰后，孵化率显著降低；幼虫期fuca基因被干扰后，寿命与运动能力显著下降，并且发育为雌虫的成虫产卵量下降。上述结果表明，fuca基因在松材线虫发育、寿命和繁殖过程中均起着重要的作用。

国家林业和草原科学数据中心2022-11-01 更新140

Elucidating the role of OsMyb-R1 in Arabidopsis under drought stress using RNA-Seq approach among over-expressing and wild-type plants

基因功能

抗旱性

In this study, we targeted Myb TF to functionally characterize its role in imparting abiotic stress tolerance, particularly in drought, using the gain of function approach. Ectopic expression of OsMyb

NIAID Data Ecosystem60

A haploid gene-trap mutant collection enables functional genetics in human cells

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