Cathepsin K complexed with a ketoamide inhibitor
收藏Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/1tu6
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Cathepsin K complexed with a ketoamide inhibitor Descriptor: Cathepsin K, SULFATE ION, [1-(4-FLUOROBENZYL)CYCLOBUTYL]METHYL (1S)-1-[OXO(1H-PYRAZOL-5-YLAMINO)ACETYL]PENTYLCARBAMATE Authors: Barrett, D.G, Catalano, J.G, Deaton, D.N, Hassell, A.M, Long, S.T, Miller, A.B, Miller, L.R, Shewchuk, L.M, Wells-Knecht, K.J, Wright, L.L. Deposit date: 2004-06-24 Release date: 2004-09-21 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Potent and selective P2-P3 ketoamide inhibitors of cathepsin K with improved pharmacokinetic properties via favorable P1', P1, and/or P3 substitutions BIOORG.MED.CHEM.LETT., 14, 2004
创建时间：
2004-06-24
