Effect of whole-body deletion of Gclc on the liver
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https://www.ncbi.nlm.nih.gov/sra/SRP499654
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资源简介：
The rate-limiting step in glutathione (GSH) synthesis is controlled by glutamate-cysteine ligase catalytic subunit. To investigate the impact of GSH in vivo, we induced a deletion of Gclc using a Gclcf/f Rosa26-CreERT2 mouse model and harvested liver tissue for analysis. Overall design: Liver tissue was harvested from WT and KO mice approximately two weeks after treatment with tamoxifen to induce Cre activity and Gclc deletion.
创建时间：
2024-08-17
