Analysis of miRNA profiles in mucinous ovarian cancer cells that silenced PRKRA.. Analysis of miRNA profiles in mucinous ovarian cancer cells that silenced PRKRA.

We compared miRNAs expression in mucinous ovarian cancer cell between treated with siPRKRA and contrl siRNA. We hypothesize that PRKRA regulates chemosensitivity in mucinous ovarian cancer. Therefore, we aim to idetify the PRKRA-mediated miRNA which regulate chemosensitivity in mucinous ovarian cancer. Overall design: We analyzed human ovarian mucinous cancer cells by Nanostring, and validated microRNA profiles after silencing PRKRA.