Data from: Exploratory GWAS of BUN in Elite Winter Sports Athletes

Title: Dataset for "Exploratory Genome-Wide Association Study of Blood Urea Nitrogen Levels in Elite Chinese Winter Sports Athletes" Description:This dataset supports the findings of the above-mentioned manuscript, which investigates genetic variants associated with blood urea nitrogen (BUN) levels in elite Chinese winter sports athletes using genome-wide association study (GWAS) methodology. The dataset includes:- GWAS summary statistics for 27 SNPs associated with BUN levels (P < 1 × 10⁻⁵)- Functional annotations including eQTL/sQTL results (GTEx v8)- Pathway enrichment analysis results based on Reactome database File: BUN GWAS_data_package.xlsx Contents:- Sheet 1 (GWAS_Summary): SNP ID, chromosome, position, P-value, beta (effect size), R² (variance explained), associated gene- Sheet 2 (QTL_Annotation): Tissue-specific eQTL and sQTL annotations for candidate SNPs from GTEx- Sheet 3 (Pathway_Enrichment): Enriched biological pathways and mapped genes using Reactome Methodology:- Genotyping was performed using Illumina Infinium array and whole-genome sequencing- Association analysis was conducted in PLINK 1.9, adjusted for sex, sport, and top 10 principal components- Functional annotations were derived using SNPnexus and GTEx v8- Pathway analysis was performed using the Reactome online tool Recommended Citation:If you use this dataset, please cite:Mei T. et al., "Exploratory Genome-Wide Association Study of Blood Urea Nitrogen Levels in Elite Chinese Winter Sports Athletes", submitted to Gene, 2025. License:CC-BY 4.0 (Creative Commons Attribution 4.0 International) Contact:Corresponding author: Zihong He ([e-mail]), Tao Mei ([e-mail]) Funding: This work was supported by:- National Key R&D Program of China (2018YFF0300402)- Fundamental Research Funds for the Central Universities (2024JNPD003) 10.5281/zenodo.16788524