Effects on peripherally administered IFNa on microglial gene expression was investigated by bulk RNA sequencing on FACS sorted microglia. The dependency of microglial Ifnar1 on signal transduction was
3D viSNE representation of microglial modules: DAM (Red) and Homeostatic (Black) genes identified by single-cell RNAseq mapped to WGCNA modules. (HTML 3818 kb)
Peripherally derived macrophages infiltrate the brain after bone marrow transplantation and during central nervous system (CNS) inflammation. It was initially suggested that these engrafting cells wer
Acute Myeloid Leukemia (AML) has been associated with somatic mutations in numerous genes; however, the penetrance of these mutations is low. Here we investigate the contribution of alternative splici
Gene expression of glia (astrocytes, microglia, oligodendrocytes, and OPCs) from Rag2-/- mice and immunocompetent controls, quantified by transcripts per million (TPM). (XLSX)