PDGFRA T674I mutant kinase domain in complex with avapritinib derivative 9
收藏Protein Data Bank Japan2024-08-07 更新2026-04-25 收录
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https://pdbj.org/mine/summary/8pqi
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资源简介：
PDGFRA T674I mutant kinase domain in complex with avapritinib derivative 9 Descriptor: (1~{S})-~{N}-ethyl-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine, DI(HYDROXYETHYL)ETHER, Platelet-derived growth factor receptor alpha Authors: Teuber, A, Kleinboelting, S, Mueller, M.P, Rauh, D. Deposit date: 2023-07-11 Release date: 2023-12-27 Last modified: 2024-08-07 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nat Commun, 15, 2024
创建时间：
2023-07-11
