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smallRNA-Seq analysis comparing p53-null versus ?Np63?/?;p53-null thymic lymphoma tumors

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https://www.ncbi.nlm.nih.gov/sra/SRP070067
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资源简介:
We performed a smallRNA-Seq analysis comparing thymic lymphoma tissues from the p53-null (n=4) and ?Np63?/?;p53-/- (n=3). Mice at 10 weeks of age were injected with either Ad-mCherry or Ad-CRE-mCherry to delete ?Np63 in the thymic lmyphomas. We aimed to test by deleting the ?Np63 in these p53-deficient tumors will mediate tumor regression and analyze the expression profile of the small RNAs Overall design: Examination of thymic lymphoma tissues in 2 different genotypes (p53-/- vs ?Np63?/?;p53-/-)
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2017-09-17
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