We report the consequences of the disruption of the Fmo5 gene on transcription of genes in liver. Comparison of liver gene expression in wild-type and Fmo5(-/-) mice
LRRC10 is a heart-specific gene required for proper cardiac function. The effects of Lrrc10 deletion on gene expression in the embryonic mouse heart was investigated. Overall design: Pregnant heterozy
Transcriptome analysis (mRNA sequencing) of mouse livers isolated from 10-month-old male and female Tlcd1/2 double knockout mice, fed either chow diet, high fat diet (60% kcal fat) or Western diet (45
Peeling Skin Disease (PSD; OMIM 270300) is an inflammatory ichthyosis due to homozygous loss-of-function mutations in Corneodesmosin (CDSN) and characterized by lifelong patchy peeling of the skin ass
In rats, direct exposure to TCDD causes myriad toxicities. Exposed rats experience hepatotoxicity, wasting syndrome and immune suppression, amongst others. “Inherited exposure”, as occurs in the F3 ge