Core SEPs of the NTHia.

a Proteins were initially identified as putative members of the SEP complement using PSORT and PSORTb analysis of cellular localization of predicted protein sequences and/or due to homology to known OM localized proteins. Lists were narrowed by excluding SEPs not conserved across the sequenced NTHi isolates and removal of proteins that lacked a strong probability of being localized to the outer membrane and having surface exposed residues.b Probable structure based on modeling. PRED-TMBB and BOMP (β-barrel), TMHMM (α-helix), amorphous for proteins that fit neither model or have components of both. Bolding indicates proteins that have been modelled and for which conserved peptideshave been identified (see S1 Table).Core SEPs of the NTHia.