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Diastereoselective Intermolecular Cobalt-Catalyzed Reductive Aldol Reactions of α,β-Unsaturated Amides with Ketones

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https://figshare.com/articles/dataset/Diastereoselective_Intermolecular_Cobalt_Catalyzed_Reductive_Aldol_Reactions_of_Unsaturated_Amides_with_Ketones/2981722
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资源简介:
Under cobalt catalysis, diethylzinc mediates the conjugate reduction of α,β-unsaturated amides to produce ethylzinc enolates that react with ketones in situ to produce tertiary alcohol-containing aldol products with up to >19:1 diastereoselectivity.
创建时间:
2016-06-03
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