Total Synthesis of (−)-Ambiguine P
收藏Figshare2019-03-13 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Total_Synthesis_of_-Ambiguine_P/7841111
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Described is a concise total synthesis of (−)-ambiguine P, a cycloheptane-containing member of the hapalindole alkaloids. The challenging pentacyclic framework of the natural product was assembled rapidly via a [4 + 3] cycloaddition reaction-inspired strategy, and the tertiary hydroxy group was introduced by an NBS-mediated bromination–nucleophilic substitution sequence.
创建时间:
2019-03-13



