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Identifying blood transcriptome biomarkers of Alzheimer’s disease using transgenic mice

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE144459
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In the present study, we used 3xTg-AD mice and collected brain and blood at the same time to identify novel blood transcriptome biomarkers of AD and to validate our previous biomarkers. The 3xTg-AD male mice (n=8 at 12 w.o.a; n=8 at 52 w.o.a) and age-matched B6129SF2 WT male mice (n=8 at 12 w.o.a; n=8 at 52 w.o.a) were killed and gene expression profiles of their hippocampi and bloods were compared.
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2023-09-12
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