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Inverse data-driven modelling and multiomics analysis reveals PHGDH as a metabolic signature of M2 macrophages

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE118119
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RNAseq data from C57BL/6 bone marrow-derived macrophages that were stimulated with IL-4 in the presence or absence of the PHGDH inhibitor CBR-5884. BMDM were pre-treated with either 30 µM CBR-5884 (AxonMedchem) or solvent. Thereafter, 10 ng/ml IL-4 (Peprotech) was added and cells were harvested 24h later for RNA isolation.
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2020-02-18
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