We performed bulk RNA sequencing of tumor biopsies from patients before treatment, on-treatment and in case a poor response was suspected from the resection specimen. At baseline we found in respondin

NIAID Data Ecosystem30

TIGIT signaling blockade in ex vivo expanded NK cells in co-culture with cancer spheroids

癌症免疫治疗

细胞功能调控

TIGIT signaling in NK cells was blocked with anti-TIGIT antibody in the co-culture with cancer spheroids for 7 days. NK cells were selected upon co-culture and RNA sequencing was performed to understa

NIAID Data Ecosystem10

Data_Sheet_1_Therapeutic Bispecific T-Cell Engager Antibody Targeting the Transferrin Receptor.docx

癌症免疫治疗

双特异性抗体

Bispecific T-cell engager antibodies (BiTE) have been explored as a means to recruit cytolytic T cells to kill tumor cells. The transferrin receptor (TfR) is highly expressed on the surface of rapidly

NIAID Data Ecosystem30

Additional file 4: of Immune-enrichment of non-small cell lung cancer baseline biopsies for multiplex profiling define prognostic immune checkpoint combinations for patient stratification

癌症免疫治疗

免疫检查点

Interactive NAViGaTOR .n3e file of ICP-interactors and pathways. (N3E 958 kb)

DataCite Commons2020-08-27 更新30