Data pertaining to structural and functional analyses of NF-kB in diverse holozoan taxa

This repository contains data pertaining to sequence and structural analyses of the transcription factor NF-kB across a diverse set of holozoan species. Dataset includes data relevant to comparative sequence analyses of the NF-kB Rel homology domain (RHD), as well as comparative analyses of three-dimensional structures of this domain predicted using AlphaFold3. Further, data are included for an analysis correlating NF-kB RHD sequence and structural similarity between species with binding preference as previously quantified using protein binding microarrays (PBMs). All data are available for open use.