Imatinib disassembles the regulatory core of Abelson kinase by binding to its ATP site and not by binding to its myristoyl pocket

NMR raw 1H-15N TROSY data and processed spectra of a titration of U-15N-labeled Abl83-534 with imatinib presented in the manuscript "Imatinib disassembles the regulatory core of Abelson kinase by binding to its ATP site and not by binding to its myristoyl pocket".

1H-15N TROSY spectra were recorded at molar ratios of 0, 1:10, 3:10, 5:10, 7:10, 1:1, and 3:1 imatinib:Abl83-534 at 303 K on a Bruker Ascend 600-MHz spectrometer equipped with a TCI triple resonance cryoprobe with 140 (15N) × 1024 (1H) complex points and acquisition times of 42 ms (15N) and 48 ms (1H).

Description of files contained in DATA.zip:

A3D.DAT: raw data in NMRPipe format with the 7 titration points stored a subsequent 2D planes

B3D.DAT: processed data in NMRPipe format with the 7 titration points stored a subsequent 2D planes

xy_3D.com: NMRPipe processing script to convert A3D.DAT to B3D.DAT