five

X-ray structure of furin in complex with the dichlorophenylpyridine-based inhibitor 5

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Protein Data Bank Japan2024-10-16 更新2026-03-28 收录
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X-ray structure of furin in complex with the dichlorophenylpyridine-based inhibitor 5 Descriptor: 2-[(3S)-1-[[2-[3,5-bis(chloranyl)phenyl]-6-[2-(4-methylpiperazin-4-ium-1-yl)pyrimidin-5-yl]oxy-pyridin-4-yl]methyl]pyrrolidin-1-ium-3-yl]oxyethanoic acid, CALCIUM ION, CHLORIDE ION, ... Authors: Dahms, S.O, Brandstetter, H, Pautsch, A. Deposit date: 2022-01-27 Release date: 2022-04-13 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism. Acs Chem.Biol., 17, 2022
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2022-01-27
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