TNFRSF10A
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资源简介：
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
该基因编码的蛋白质属于TNF受体超家族。该受体由肿瘤坏死因子相关凋亡诱导配体（TNFSF10/TRAIL）激活，从而传递细胞死亡信号并诱导细胞凋亡。对FADD缺陷小鼠的研究表明，FADD，一种含有死亡结构域的适配蛋白，对于该蛋白介导的凋亡过程是必需的。[由RefSeq提供，2008年7月]
提供机构：
Rat Genome Database
