HRVFIT2 study database

The aim of this study was to verify the superiority of high-intensity interval training (HIIT) to enhance parasympathetic activity, cardiorespiratory fitness and cardiac function when compared to moderate intensity continuous training (MICT) in a short and intense cardiac rehabilitation program (RP).
Methods: This is a prospective, monocentric, evaluator-blinded, randomized (1 :1) study with a two arm parallel group design. 31 voluntary chronic heart failure (CHF) patients (LVEF < 45 %) were included either to MICT (n=15) or HIIT group (n=16) for a short RP (27 ± 4 days). They underwent, at entry and at the end of the study, a 24-hour ECG recording, an echocardiography and a cardiopulmonary exercise test. Results: The High-Frequency power (HFnu, %) measured with HRV increased in HIIT group (from 21.2 to 26.4 %, p<0.001) but remained unchanged in MICT group (from 23.1 to 21.9 %, p=0.444) with significant inter-group difference: p=0.003. Resting heart rate (24-h Holter ECG) decreased significantly in both groups (from 68.2 to 64.6 bpm and from 66.0 to 63.5 bpm for MICT and HIIT respectively, without inter-group difference: p=0.578). No difference in premature ventricular contractions was observed between groups. V̇O2peak improvement was greater after HIIT when compared to MICT (+21 % vs +5% respectively, p=0.009). LVEF only improved in HIIT group (from 36.2 to 39.5 %, p=0.034).

本研究旨在验证高强度间歇训练（HIIT）相较于中等强度持续训练（MICT）在短时间内增强副交感神经活动、心肺适能及心脏功能方面的优越性。研究方法为前瞻性、单中心、评估者盲法、随机分配（1:1）的两臂平行分组设计。纳入31名自愿参与的慢性心力衰竭（CHF）患者（左心射血分数LVEF＜45%），分别分配至MICT组（n=15）或HIIT组（n=16），进行为期27±4天的短期康复计划（RP）。在研究开始和结束时，受试者均接受24小时心电图记录、超声心动图检查和心肺运动测试。研究结果：使用心率变异性（HRV）测量的高频功率（HFnu，%）在HIIT组中显著增加（从21.2%增至26.4%，p＜0.001），而在MICT组中则保持不变（从23.1%增至21.9%，p=0.444），两组间存在显著差异：p=0.003。两组的静息心率（24小时Holter心电图）均显著降低（MICT组从68.2次/分钟降至64.6次/分钟，HIIT组从66.0次/分钟降至63.5次/分钟，组间无显著差异：p=0.578）。两组间未观察到早搏的差异。与MICT组相比，HIIT组在V̇O2peak的改善方面更为显著（+21% vs +5%，p=0.009）。仅HIIT组LVEF有所改善（从36.2%增至39.5%，p=0.034）。

搜集汇总

背景与挑战

背景概述

该数据集包含了一项关于高强度间歇训练（HIIT）和中等强度持续训练（MICT）对慢性心力衰竭患者心率变异性、心肺功能和心脏功能影响的比较研究数据。研究结果显示，HIIT在提高副交感神经活动和心肺功能方面优于MICT，且左心室射血分数（LVEF）仅在HIIT组有所改善。