Statistical analyses of the results in MRE prediction before and after filtering with the central loop score

TP: true positive; FP: false positive; FN: false negative; TN: true negative.; 1.Old criteria: seed homology plus minimum free energy kcal/mol, not filtered by the central loop score. Detailed description can be found in the Methods section.2.New criteria: seed homology plus free energy kcal/mol, filtered by the central loop score.3.Gold Standard: Luciferase activity assay.4.**: The specificity comparison between old criteria and new criteria shows a significant difference (p