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Human nuclear Dicer restricts the deleterious accumulation of endogenous double strand RNA

ChEBI2014-04-10 更新2026-07-21 收录

RNA干扰机制

内源性双链RNA调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-56648 数据链接链接失效反馈

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Human nuclear Dicer restricts the deleterious accumulation of endogenous double strand RNA

应用场景：

创建时间：

2014-04-10

RNA干扰机制

RNA运输

RNA interference targets aberrant transcripts with cognate small interfering RNAs, which are derived from double-stranded RNA precursors. Several functional screens have identified Drosophila Blanks a

NIAID Data Ecosystem120

Degradome sequencing from S. castellii. Naumovozyma castellii

RNA干扰机制

Argonaute蛋白功能

The RNA-induced silencing complex, comprising Argonaute and guide RNA, mediates RNA interference. Here we report the 3.2 Å crystal structure of Kluyveromyces Argonaute (KpAGO) fortuitously complexed w

NIAID Data Ecosystem80

Structural insights into small RNA sorting and mRNA binding by Arabidopsis Ago domains

RNA干扰机制

蛋白质-RNA相互作用

Structural insights into small RNA sorting and mRNA binding by Arabidopsis Ago domains Descriptor: Protein argonaute 1, SULFATE ION Authors: Yuan, Y.A, Zha, X. Deposit date: 2012-01-11 Release date: 2

Protein Data Bank Japan2024-03-20 更新40

The structure of human Argonaute-2 in complex with miR-20a

蛋白质-RNA复合物结构

RNA干扰机制

Argonaute proteins lie at the heart of the RNA-Induced Silencing Complex (RISC), wherein they use small RNA guides to recognize targets. Some Argonaute proteins can directly cleave their targets, wher

NIAID Data Ecosystem100

DEPS-1 promotes P granule assembly and RNA interference in C. elegans germ cells

昆虫生殖细胞发育

RNA干扰机制

P granules are germ-cell-specific cytoplasmic structures containing RNA and protein and required for proper germ cell development in C. elegans. A new P-granule-associated protein, DEPS-1, whose loss

Alliance of Genome Resources50

Human nuclear Dicer restricts the deleterious accumulation of endogenous double strand RNA

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