4D label-free quantitative proteomics of primary treatment-naive small cell lung cancer (SCLC) tumors and paired normal adjacent tissues
收藏国家人口健康科学数据中心2026-04-18 收录
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https://www.ncmi.cn/phda/dataDetails.do?id=CSTR:17970.11.A001G.202603.100.V1.0
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资源简介：
Proteomic analysis was performed on 12 pairs of treatment-naive primary small cell lung cancer (SCLC) tumors and matched normal adjacent tissues (NATs) using 4D label-free quantitative HPLC-MS/MS. Briefly, proteins were extracted from frozen tissue samples, digested into peptides, and analyzed on a Q Exactive HF-X mass spectrometer coupled with an EASY-nLC 1200 system. Raw data were searched against the UniProt Human database using MaxQuant (v2.2.1.0), and differential proteins were identified using Perseus software with thresholds of |log2FC| > 1 and P < 0.05.
提供机构：
北京蛋白质组研究中心
创建时间：
2026-03-25
