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Peak allelic associations within genomic regions of sarcoidosis ancestry linkage after adjustment for both global and local West African ancestry and corresponding MIX score results.

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NIAID Data Ecosystem2026-03-08 收录
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https://figshare.com/articles/dataset/_Peak_allelic_associations_within_genomic_regions_of_sarcoidosis_ancestry_linkage_after_adjustment_for_both_global_and_local_West_African_ancestry_and_corresponding_MIX_score_results_/971982
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Abbreviations: fCEU: frequency of modeled allele in HapMap Northern and Western European ancestry population; fAFR: frequency of modeled allele in HapMap Yoruban African ancestry population; fAFF: frequency of modeled allele in sarcoidosis-affected individuals; fUNF: frequency of modeled allele in unaffected individuals; OR: odds ratio; 95%CI: 95% confidence interval; P: p-value; MIX: MIXSCORE test. 1Minor allele in African Americans is bolded; modeled by generalized estimating equations adjusting for percent global West African ancestry and sex. 2“Imputed” Indicates a SNP that was imputed rather than directly genotyped. Accuracy of imputation was assessed for SNPs with p-values<10−5 in a sub-sample, and for each SNP; agreements overall and by genotype are reported in Table S2. Overall accuracy of imputation was 98.7% (rs62158012) and 98.0% (rs6502976). 3No carriers of the T allele of rs78512816 exist within HapMap and 1000 Genomes Project European populations.
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2014-03-24
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