Sensitivity analysis: Comparison between carriers and noncarriers of normal weight versus obesity after removing rs1367004987, rs775382722, and Affx-89021050.

Values are expressed in SD scores (i.e., we calculated residuals after adjusting for age and the first 10 PC in men and women, followed by inverse normal transformation to a distribution with mean of 0 and SD of 1). Cochran–Armitage test for trend was used to compare carriers and noncarriers as well as individuals of normal weight and with obesity for IPAQ, comparative body size at age 10 years and comparative height at age 10 years. P values are reported for adjusted means for age, sex, and 10 PCs. IPAQ, International Physical Activity Questionnaire; MET, metabolic equivalent minutes; PC, principle component; PRSBMI, standardized scores of the polygenic risk score of BMI with mean 0 and SD of 1; SD, standard deviation. (XLSX)