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ZEB1 expression prevents DNA replication stress in cancer stem cells and delays chromosomal instability

ChEBI2015-12-31 更新2026-07-12 收录

癌干细胞生物学

基因组稳定性

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-56031 数据链接链接失效反馈

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ZEB1 expression prevents DNA replication stress in cancer stem cells and delays chromosomal instability

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创建时间：

2015-12-31

表观遗传调控

基因组稳定性

Histone H3.3 is a highly conserved histone H3 replacement variant in metazoans, and has been implicated in many important biological processes including cell differentiation and reprogramming. Germlin

NIAID Data Ecosystem80

DNA damage repair in barley following double-strand breaks and its dependence on ATR

DNA损伤修复

基因组稳定性

Maintaining genome integrity presents a particular challenge for plants due to their sedentary lifestyle, which disables direct avoidance of unfavorable external conditions. Additionally, plants’ meta

NIAID Data Ecosystem50

Transcriptome analysis by RNA-Seq of spp381-ts mutant

RNA剪接调控

基因组稳定性

THO/TREX is a conserved complex with a role in messenger ribonucleoprotein biogenesis that links gene expression and genome instability. Here we show that human THO interacts with MFAP1, a spliceosome

NIAID Data Ecosystem40

The self-renewal of gastric cancer stem cells is regulated by a specific collaboration between the microenvironment and the genetic condition.. Homo sapiens

癌干细胞生物学

癌症基因组数据

Because cancer stem cells already had genetic and epigenetic alterations which can affect the self-renewal, we tried to characterize genetic and epigenetic changes of the gastric cancer stem cells. To

NIAID Data Ecosystem60

BLM prevents instability of structure-forming DNA sequences at common fragile sites

基因组稳定性

DNA修复

Genome instability often arises at common fragile sites (CFSs) leading to cancer-associated chromosomal rearrangements. However, the underlying mechanisms of how CFS protection is achieved is not well

Figshare2018-12-11 更新50

ZEB1 expression prevents DNA replication stress in cancer stem cells and delays chromosomal instability

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