Raw diffraction images of the first bromodomain of human BRD4 in complex with (+)-JD1

Raw diffraction images of the first bromodomain of human BRD4 in complex with (+)-JD1, an Organometallic BET Bromodomain Inhibitor. The final structure is deposited in the Protein Data Bank under accession code 6SE4. The structure is part of the following publication: Hassell-Hart, S., Runcie, A., Krojer, T., Doyle, J., Lineham, E., Ocasio, C.A., Neto, B.A.D., Fedorov, O., Marsh, G., Maple, H., et al. (2019). Synthesis and Biological Investigation of (+)-JD1, an Organometallic BET Bromodomain Inhibitor. Organometallics. doi: 10.1021/acs.organomet.9b00750. Additional information: dataset: BRD4A-JD1_i03<br> beamline: Diamond Light Source I03<br> visit: mx19301-7<br> date: 25-11-2018<br> Flux: 2.03e+11<br> Ω Start: 0.0°<br> Ω Osc: 0.15°<br> Ω Overlap: 0°<br> No. Images: 1200<br> Resolution: 1.50Å<br> Wavelength: 0.9762Å<br> Exposure: 0.030s<br> Transmission: 100.00%<br> Beamsize: 80x20μm datasets: BRD4A-JD1_i04<br> beamline: Diamond Light Source I04<br> visit: mx19301-9<br> date: 08-12-2018<br> Flux: 6.62e+11<br> Ω Start: 0.0°<br> Ω Osc: 0.50°<br> Ω Overlap: 0°<br> No. Images: 720<br> Resolution: 2.30Å<br> Wavelength: 1.7384Å<br> Exposure: 0.050s<br> Transmission: 100.00%<br> Beamsize: 32x20μm Additionally, a cif file containing refinement restraints and a png file for the ligand JD1 is included.