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Crystal Structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(cyclohexylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+

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Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Crystal Structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(cyclohexylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+ Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... Authors: Aripirala, S, Amzel, L.M, Gabelli, S.B. Deposit date: 2012-03-01 Release date: 2013-01-16 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (3.05 Å) Cite: Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. J.Med.Chem., 55, 2012
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2012-03-01
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