Gene expression-based analysis of neural tube closure for the posterior neuropore of Fkbp8 embryos at E9.5

Three wildtype and three nullizygous embryonic posterior neural tube tissues were collected at embryonic day 9.5 and the gene expression patterns were profiled on CodeLink Mouse Whole Genome Bioarrays. Wild type versus nullizygous Fkbp8 embryonic tissues were compared individually and as separate groups to determine classifiers and differences in expression due to the nullizygous mutation.于胚胎发育第9.5天收集3份野生型（wildtype）与3份纯合缺失型胚胎后神经管组织，并采用CodeLink小鼠全基因组生物芯片（CodeLink Mouse Whole Genome Bioarrays）对其基因表达模式进行了表达谱分析。将野生型与纯合缺失型Fkbp8（FK506结合蛋白8）胚胎组织分别进行个体比对及分组比对，以确定由该纯合缺失突变引发的表达分类特征及表达差异。