Structure of drug-resistant V27A mutant of the influenza M2 proton channel bound to spiroadamantyl amine inhibitor
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Structure of drug-resistant V27A mutant of the influenza M2 proton channel bound to spiroadamantyl amine inhibitor Descriptor: (1r,1'S,3'S,5'S,7'S)-spiro[cyclohexane-1,2'-tricyclo[3.3.1.1~3,7~]decan]-4-amine, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, ... Authors: Thomaston, J.L, Liu, L, DeGrado, W.F. Deposit date: 2019-02-04 Release date: 2020-01-15 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: X-ray Crystal Structures of the Influenza M2 Proton Channel Drug-Resistant V27A Mutant Bound to a Spiro-Adamantyl Amine Inhibitor Reveal the Mechanism of Adamantane Resistance. Biochemistry, 59, 2020
创建时间：
2019-02-04
