Lis1 mutant is more dissimilar to WT than Ndel1 by WGCNA.

Co-expression analysis of the individual genotypes (Lis1cko/ko, WTa, Ndel1cko/ko, WTb) revealed more severe differences in the clustering of Lis1 than Ndel1 mutants compared to WT. * and ↑ and colors refer to Figure 2E, 2F. In Lis1cko/ko: Module 1a (M1a) represents S-phase and Mitosis (Sc = 8.3 and Sc = 6.2); Module 1b (M1b) represents Mitosis and S-phase (Sc = 21.8 and Sc = 15.2); Synaptogenesis is represented by Module 2 (M2-light yellow, Sc>13.6); Translation is represented by two Modules 3 (M3-green, Sc = 13.3); 9 Modules with Sc>3 (Ms, see for examples ↑ in Figure 2E); Axonal guidance module is light green (Sc = 4.2); Inflammation module is black (Sc = 3.5). In WTa: Module 1 (M1) represents Mitosis and S-phase (Sc = 25.8 and Sc = 24.8); Synaptogenesis is represented by Module 2 (M2-yellow, Sc>10.5); Translation is represented by Module 3 (M3-blue, Sc = 21.1); Proteolysis module is green (Sc = 3.3); WNT signaling module is salmon (Sc = 3.4); Reproduction module is pink (Sc = 3.6). In Ndel1cko/ko: Cell cycle module (M1-blue) is similar to WTb and includes also translation processes (Sc = 32.1); Protein folding/Immune and Blood vessels processes are represented by module green and red (3>Sc