CDK8-CYCC IN COMPLEX WITH 8-[3-(3-Amino-1H-indazol-6-yl)-5-chloro- pyridine-4-yl]-2,8-diaza-spiro[4.5]decan-1-one

Protein Data Bank Japan2024-05-08 更新2026-03-21 收录

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https://pdbj.org/mine/summary/5fgk

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CDK8-CYCC IN COMPLEX WITH 8-[3-(3-Amino-1H-indazol-6-yl)-5-chloro- pyridine-4-yl]-2,8-diaza-spiro[4.5]decan-1-one Descriptor: 1,2-ETHANEDIOL, 8-[3-(3-azanyl-2~{H}-indazol-6-yl)-5-chloranyl-pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one, Cyclin-C, ... Authors: Musil, D, Blagg, J, Mallinger, A. Deposit date: 2015-12-20 Release date: 2016-02-03 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19. J.Med.Chem., 59, 2016

创建时间：

2015-12-20