The binding pattern of HOXA5 in the genome of extrahepatic cholangiocarcinoma cells

HOXA5 is a transcription factor in mammalian and can regulate cell differentiation, proliferation and apoptosis as well as tumorigenesis. However, little is known on whether and how HOXA5 can regulate the malignant behaviors of cholangiocarcinoma. The binding pattern of HOXA5 was evaluated by CUT & Tag assay. The differential peaks were analysed to assess the role of HOXA5 in the regulation of the key genes involved in cell proliferation and DNA replication. Overall design: Immunoprecipitation was performed with anti-Flag antibodies. This dataset includes two CUT & Tag samples. One is TFK-1 cell sample that treated with HOXA5 overexpression vector and the other is TFK-1 cell sample that treated with normal control vector.