Cellular toxicity and inhibitory concentration of anti-influenza extracts against H3N1 and H1N1 strains.

CC50a represents the concentration of plant extract required to reduce the number of viable cells by 50% relative to control wells without test compound, calculated from dose–response data, CC50 value estimated using regression analysis was greater than the highest tested concentration (>100 µg/mL). In this case, the result was an estimated theoretical value obtained by extrapolation of the results in Figure 1.IC50b represents the concentration of plant extract needed to reduce the viral inhibition by 50% relative to virus control wells without test compound, calculated from dose–response data of virus inhibition. Plant extracts (0.78–100 µg/mL) in RPMI medium were challenged with 100 TCID50 of either of the two virus strains.